DOI: 10.1007/s00259-018-4070-8Pages: 2009-2024

Guidelines on nuclear medicine imaging in neuroblastoma

1. Tel Aviv University, Schneider Children’s Medical Center

2. Great Ormond Street Hospital for Children NHS Foundation Trust

3. St Jude Children’s Research Hospital

4. Peter MacCallum Cancer Centre

5. Humanitas Clinical and Research Hospital, Department of Nuclear Medicine

6. Linköping University, Department of Radiology and Department of Medical and Health Sciences

7. Istituto Nazional Tumori

8. Clinique de la Source

9. Radiology and Nuclear Medicine Ghent University, Department of Nuclear Medicine Maria Middelares Hospital

10. Ludwig Maximilian University Hospital

11. British Columbia Children’s Hospital

12. Cincinnati Children’s Hospital Medical Center

13. International Atomic Energy Agency, Nuclear Medicine and Diagnostic Imaging Section

Correspondence to:
Zvi Bar-Sever
Email: barsever@clalit.org.il

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Abstract

Nuclear medicine has a central role in the diagnosis, staging, response assessment and long-term follow-up of neuroblastoma, the most common solid extracranial tumour in children. These EANM guidelines include updated information on 123I-mIBG, the most common study in nuclear medicine for the evaluation of neuroblastoma, and on PET/CT imaging with 18F-FDG, 18F-DOPA and 68Ga-DOTA peptides. These PET/CT studies are increasingly employed in clinical practice. Indications, advantages and limitations are presented along with recommendations on study protocols, interpretation of findings and reporting results.

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  • Online: Jun 25, 2018

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