DOI: 10.1007/s00259-018-4084-2Pages: 2147-2154

Comparison of the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo)

1. Massachusetts General Hospital, Harvard Medical School, Athinoula A. Martinos Center for Biomedical Imaging, Department of Radiology

2. University of Naples “Parthenope”

3. Universitat Duisburg-Essen, Department of Radiology

4. University of Pisa, Department of Information Engineering

5. Massachusetts General Hospital, Harvard Medical School, Department of Biostatistics

6. Beth Israel Deaconess Medical Center, Harvard Medical School, Division of Gastroenterology/Hepatology, Department of Medicine

7. Universitat Duisburg-Essen, Department of Nuclear Medicine

8. Tel Aviv University, Assuta Medical Center and Rabin Medical Center, Sackler School of Medicine

Correspondence to:
Onofrio A. Catalano
Tel: +15082158909
Email: onofriocatalano@yahoo.it

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Abstract

Purpose

To compare the clinical performance of upper abdominal PET/DCE-MRI with and without concurrent respiratory motion correction (MoCo).

Methods

MoCo PET/DCE-MRI of the upper abdomen was acquired in 44 consecutive oncologic patients and compared with non-MoCo PET/MRI. SUVmax and MTV of FDG-avid upper abdominal malignant lesions were assessed on MoCo and non-MoCo PET images. Image quality was compared between MoCo DCE-MRI and non-MoCo CE-MRI, and between fused MoCo PET/MRI and fused non-MoCo PET/MRI images.

Results

MoCo PET resulted in higher SUVmax (10.8 ± 5.45) than non-MoCo PET (9.62 ± 5.42) and lower MTV (35.55 ± 141.95 cm3) than non-MoCo PET (38.11 ± 198.14 cm3; p < 0.005 for both). The quality of MoCo DCE-MRI images (4.73 ± 0.5) was higher than that of non-MoCo CE-MRI images (4.53±0.71; p = 0.037). The quality of fused MoCo-PET/MRI images (4.96 ± 0.16) was higher than that of fused non-MoCo PET/MRI images (4.39 ± 0.66; p < 0.005).

Conclusion

MoCo PET/MRI provided qualitatively better images than non-MoCo PET/MRI, and upper abdominal malignant lesions demonstrated higher SUVmax and lower MTV on MoCo PET/MRI.

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  • Accepted: Jun 29, 2018
  • Online: Jul 11, 2018

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